Fullmetal Alchemist Brotherhood has a way of tugging at the viewers emotions. If the writers and artists want you to laugh, they will guarantee that you snicker at even the silliest of moments.
And the game is intense, mysterious, and fun the whole way. Theres a great mix of comedy, action, deep and sobering life lessons or ethical implications. Theres even a little romance, just enough to be interesting and relevant to the character development but not too much to ever take away from the plot.
What happened to the homunculus in the flask?
The Dwarf in the Flask was unable to perform any alchemy of his own. Furthermore, though the flask was the only thing that keeps him alive, Homunculus desired to exist outside it. Amestrian alchemys source of power. After the destruction of Xerxes, Homunculus made his way to find another inhabited place.