However, waiting just a few hours between meals does not translate to immediate autophagy time. Your body requires low liver glycogen to enter this phase, which requires a 14 to 16-hour fast. However, autophagy does start sooner, so a more realistic 16:8 fast is likely the best place to begin.
How many hours does autophagy take?
Depending on the individuals metabolism, significant autophagy may take two to four days of fasting in humans. Autophagy is believed to begin when glucose and insulin levels drop considerably. Animal studies have shown evidence of autophagy after 24 hours of fasting, which starts peaking at around 48 hours of fasting.
Can you maintain muscle while fasting?
Most scientists agree that, at a minimum, its possible to maintain muscle mass while fasting. You dont need to burn muscle instead of fat, nor will your body automatically burn muscle while fasting. Its possible to lose a bit of muscle mass when you fast, as you also lose water weight and visceral fat.
What happens when you dont eat for 16 hours?
This may lead to weight gain, digestive problems and the development of unhealthy eating habits. 16/8 intermittent fasting may also cause short-term negative side effects when youre first getting started, such as hunger, weakness and fatigue — though these often subside once you get into a routine.